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Niranjan Y Sardesai Selected Research

DNA Vaccines

1/2018Broad cross-protective anti-hemagglutination responses elicited by influenza microconsensus DNA vaccine.
1/2018Gag and env conserved element CE DNA vaccines elicit broad cytotoxic T cell responses targeting subdominant epitopes of HIV and SIV Able to recognize virus-infected cells in macaques.
1/2018DNA Vaccine-Induced Long-Lasting Cytotoxic T Cells Targeting Conserved Elements of Human Immunodeficiency Virus Gag Are Boosted Upon DNA or Recombinant Modified Vaccinia Ankara Vaccination.
1/2017A Novel DNA Vaccine Platform Enhances Neo-antigen-like T Cell Responses against WT1 to Break Tolerance and Induce Anti-tumor Immunity.
1/2016In vivo protection against ZIKV infection and pathogenesis through passive antibody transfer and active immunisation with a prMEnv DNA vaccine.
11/2015Safety, efficacy, and immunogenicity of VGX-3100, a therapeutic synthetic DNA vaccine targeting human papillomavirus 16 and 18 E6 and E7 proteins for cervical intraepithelial neoplasia 2/3: a randomised, double-blind, placebo-controlled phase 2b trial.
8/2015Skin Transfection Patterns and Expression Kinetics of Electroporation-Enhanced Plasmid Delivery Using the CELLECTRA-3P, a Portable Next-Generation Dermal Electroporation Device.
1/2015Novel synthetic plasmid and Doggybone DNA vaccines induce neutralizing antibodies and provide protection from lethal influenza challenge in mice.
10/2014An optimized, synthetic DNA vaccine encoding the toxin A and toxin B receptor binding domains of Clostridium difficile induces protective antibody responses in vivo.
5/2014Protective immunity to H7N9 influenza viruses elicited by synthetic DNA vaccine.
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Niranjan Y Sardesai Research Topics

Disease

20Infections
01/2018 - 10/2009
12Human Influenza (Influenza)
01/2018 - 06/2008
11Neoplasms (Cancer)
06/2021 - 05/2006
6Communicable Diseases (Infectious Diseases)
11/2018 - 06/2011
3Uterine Cervical Dysplasia
01/2018 - 10/2012
3Vaccinia
01/2018 - 11/2014
3Pneumonia (Pneumonitis)
01/2017 - 10/2013
2Weight Loss (Weight Reduction)
12/2017 - 01/2016
2Viremia
12/2017 - 02/2013
2Carcinoma (Carcinomatosis)
12/2017 - 05/2006
2Pain (Aches)
11/2017 - 10/2012
2Rheumatoid Arthritis
03/2016 - 08/2014
2Virus Diseases (Viral Diseases)
01/2016 - 01/2011
2Emerging Communicable Diseases (Emerging Infectious Diseases)
01/2016 - 05/2014
2Dengue (Dengue Fever)
07/2015 - 10/2009
2HIV Infections (HIV Infection)
03/2015 - 06/2012
2Malaria
01/2014 - 06/2012
2Inflammation (Inflammations)
06/2012 - 02/2012
1Male Infertility (Male Sterility)
01/2019
1Ebola Hemorrhagic Fever
11/2018
1Lassa Fever (Fever, Lassa)
12/2017
1Prostatic Neoplasms (Prostate Cancer)
12/2017
1Bacterial Infections (Bacterial Infection)
01/2017
1Zika Virus Infection
01/2016
1Erythema
11/2015
1Injection Site Reaction
11/2015
1Acquired Immunodeficiency Syndrome (AIDS)
08/2015
1Rubella (German Measles)
04/2015
1Breakthrough Infections
01/2015
1Fever (Fevers)
01/2015
1Diarrhea
10/2014
1Colonic Diseases
10/2014
1Pleurisy (Pleuritis)
08/2014
1Autoimmune Diseases (Autoimmune Disease)
08/2014
1Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
08/2014
1Systemic Lupus Erythematosus (Libman-Sacks Disease)
08/2014
1Type 1 Diabetes Mellitus (Autoimmune Diabetes)
08/2014
1Hepatitis C
01/2014
1Chronic Hepatitis C
09/2013
1Papillomavirus Infections
03/2013
1Experimental Melanoma
03/2013
1Congenital Abnormalities (Deformity)
11/2012
1Tuberculosis (Tuberculoses)
06/2012
1Smallpox (Variola)
01/2011
1Mpox (monkeypox)
01/2011

Drug/Important Bio-Agent (IBA)

30VaccinesIBA
06/2021 - 10/2009
22DNA (Deoxyribonucleic Acid)IBA
06/2021 - 06/2008
19DNA VaccinesIBA
01/2018 - 10/2009
10AntigensIBA
06/2021 - 06/2008
7A-Form DNA (A-DNA)IBA
01/2019 - 01/2011
7Proteins (Proteins, Gene)FDA Link
01/2018 - 05/2006
4Monoclonal AntibodiesIBA
11/2018 - 01/2017
4InterferonsIBA
01/2016 - 08/2012
3Immunoglobulin G (IgG)IBA
01/2017 - 02/2013
3NucleoproteinsIBA
10/2013 - 09/2011
2EpitopesIBA
06/2021 - 01/2018
2Glycoproteins (Glycoprotein)IBA
11/2018 - 05/2014
2VGX-3100IBA
01/2018 - 11/2015
2Biomarkers (Surrogate Marker)IBA
01/2018 - 04/2007
2AIDS VaccinesIBA
01/2018 - 11/2017
2AntibodiesIBA
01/2017 - 09/2015
23-phenyl-4,5-dihydro-5-isoxazole acetic acidIBA
03/2016 - 08/2014
2Antiviral Agents (Antivirals)IBA
08/2015 - 10/2009
2Neutralizing AntibodiesIBA
07/2015 - 01/2015
2HLA-DR Antigens (HLA-DR)IBA
01/2015 - 05/2012
2Peptides (Polypeptides)IBA
11/2014 - 04/2007
2MesothelinIBA
04/2007 - 05/2006
1Immune Checkpoint InhibitorsIBA
01/2019
1Influenza Vaccines (Influenza Vaccine)FDA Link
01/2018
1env Gene ProductsIBA
01/2018
1ProteomeIBA
01/2018
1Neoplasm Antigens (Tumor Antigens)IBA
01/2017
1Formaldehyde (Formol)FDA Link
01/2017
1Respiratory Syncytial Virus VaccinesIBA
01/2017
1Pharmaceutical PreparationsIBA
08/2015
1Nucleic AcidsIBA
07/2015
1Rubella VaccineIBA
04/2015
1CC ChemokinesIBA
01/2015
1mRNA VaccinesIBA
01/2015
1SAIDS VaccinesIBA
11/2014
1trimethylaminocarboxyldihydroboran (TCDB)IBA
10/2014
1LipopolysaccharidesIBA
08/2014
1Toll-Like Receptor 4IBA
08/2014
1OligonucleotidesIBA
08/2014
1Acetic Acid (Vinegar)FDA LinkGeneric
08/2014
1Hemagglutinins (Hemagglutinin)IBA
05/2014
1Telomerase (Telomerase Reverse Transcriptase)IBA
09/2013
1Synthetic Vaccines (Recombinant Vaccines)IBA
03/2013
1Viral AntigensIBA
03/2013
1Interleukin-12 (IL 12)IBA
03/2013
1EnzymesIBA
10/2012
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
08/2012
1avian influenza A virus hemagglutininIBA
06/2012
1Small Interfering RNA (siRNA)IBA
02/2012
1Nucleocapsid ProteinsIBA
09/2011
1Complement System Proteins (Complement)IBA
01/2011

Therapy/Procedure

8Therapeutics
01/2019 - 03/2013
7Immunotherapy
06/2021 - 03/2013
1Injections
11/2017
1Organ Transplantation
11/2012